A Research on: Formulation and Evaluation of ...

A Research on: Formulation and Evaluation of Osmotic Release Tablet of Glipizide

Author Name : Kunal D. Jadhav, Jitendra V. Shinde, Ankita V. Bhosale, Shital A. Kasture

ABSTRACT

The controlled release systems are generally designed to exert control over drug release on the body, whether it be of a temporal, spatial, or both natures. To put it another way, the system makes an effort to control medication concentration in the tissue or cells.Drug delivery can be divided into three categories: targeted delivery, controlled release, and modulated release. In order to deliver a drug to particular cell types, tissues, or organs, a drug-carrier must be administered systemically. This is known as targeted delivery. Using a delivery system with the goal of releasing the medication into the patient's body at a specified pace, at a set time, or with a set release profile is known as controlled release. The main aim of these research paper is to formulate and evaluate osmotic release tablet of glipizide. We successfully formulate and evaluate six batches of tablet. We observed that batch F5 C is as a optimum batch as it shows 99.50% drug release.FromthebatchesF5A–F5E we have observed that some batches were good at extent of drug release & some batches were good at rate of drug.

Keyword-  FTIR, DSC, Osmotic Release, In-Vitro Release, Friability.