A Review Article on Role of Immunotherapy in ...

A Review Article on Role of Immunotherapy in Rhematoid Arthraitis Treatment: Current Trends and Future Direction

Author Name : Prof. (Dr.) Mohd.Wasiullah, Prof. (Dr.) Piyush Yadav, Dr. ShashikantMaury, Neha Yadav

ABSTRACT Rheumatoid arthritis is a chronic, systemic, abnormal inflammatory immune re-sponse. It is characterized by the involvement of the synovium and multiple organs and the destruc-tion of joints and articular cartilage. Over the past 30 years, several promising novel compounds and antibodies have been developed for the treatment of Rheumatoid arthritis. A new drugs and precision medicine for all forms of Rheumatoid arthritis raises several issues related to access to novel treatments by patients, optimal regimen selection, cost-effectiveness, prognosis monitoring and outcome surveil-lance, particularly with regarding to the development of low drug response rates, drug resistance and adverse side effects. Particularly in early high-risk vulnerable and early in-dividuals Addressing these issues requires novel therapeutic approaches with new mechanisms and the establishment of accurate guidelines for drug selection, drug recombination, and non-chemical therapeutic efforts. In this study, we reviewed the most exciting recently established or ongoing novel drugs and methods according to the clinical trial database maintained by the United States National Library of Medicine and discussed the trends in Rheumatoid arthritis development and challenges in the treatment, providing a reference significant for the accurate treatment of Rheumatoid arthritis and the research direction in the future