A Review on Stem Cell Therapy in Cancer

A Review on Stem Cell Therapy in Cancer

Author Name : Mr. Nilesh N. Shinde, Mr. Kanwate Chaitanya G, Ms. Solunke Nandini G, Ms. Kalyane Swati S, Ms. Thorat Bhagyashri V

DOI: https://doi.org/10.56025/IJARESM.2025.1304251284

ABSTRACT Traditional cancer therapies often struggle with limitations due to their broad and unspecific targeting, which can lead to therapy resistance and the recurrence of cancer. However, significant advances in stem cell biology over recent years have opened up promising avenues for potential cancer treatments. Stem cells are distinguished by their remarkable biological properties, such as self-renewal, directional migration, differentiation, and their ability to modulate the behavior of other cells. These characteristics make them useful in regenerative medicine, as therapeutic carriers, for targeted drug delivery, and in the creation of immune cells for cancer therapy. In this review, we focus on the mechanisms that underlie the application of various types of stem cells in cancer treatment. Furthermore, we provide an overview of the latest clinical advancements in stem cell-based therapies and the potential risks associated with these approaches. The emerging concept of 'cancer stem cells' has directed research efforts toward a novel and expansive area of study, revealing new potential strategies for future cancer treatments. This review primarily aims to highlight the recent breakthroughs in stem cell-based cancer therapies and delve into the role of cancer stem cells, which are now recognized as central to the development of cancer. We will also explore how these cells contribute to carcinogenesis and their potential impact on shaping future cancer treatment strategies.