A Review on synthesis and evauation of coumar...

A Review on synthesis and evauation of coumarins and its derivatives as antimicrobials

Author Name : Divya Pandey, Mayank pandey, Dr. NiharikaGokhale

ABSTRACT Coumarins contain an large group of cyclic compound obtained from plants and are manufactured from fused benzene and alpha pyrone ring. The prototypical compound is understood as 1,2 benzopyroneCoumarin has mild antibacterial activity, but long chain hydrocarbon substituted compound likeammoresinol and ostruthin show wide spectrum activity against Gram +ve bacteria like Bacillus megaterium, Micrococcusluteus, Micrococcus lysodeikticus, and Staphylococcus aureus. Another coumarin compound anthogenol from green fruits of Aeglemarmelos shows activity against Enterococcus. The target behind this review is to synthesise a brand new caumarin derivative which shows greater efficacy and potency with microbial growth.