Aerosol Pressurized Dosage Form

Aerosol Pressurized Dosage Form

Author Name : Deepak Shivpoojan Barai, Dr. Nitin C. Mohire, Harshada Dhangar, Ganeshmal Chaudhari, Ajay Thakare

ABSTRACT Pharmaceutical aerosols have gained significant attention due to rapid technological advancements. These aerosols offer targeted and efficient drug delivery, especially for respiratory conditions. Key factors influencing aerosol performance include particle size, physical properties of ingredients, formulation stability, propellant selection, valve design, and environmental factors The choice of propellant is crucial, with options including chlorofluorocarbons (CFCs), hydrocarbon (HC) propellants, compressed gas propellants, and advanced propellants like hydrofluoroalkanes (HFAs).Container type and material also play a significant role in aerosol performance, with options including glass, metals (stainless steel and aluminum), and plastics. Each material has its advantages and limitations, requiring careful consideration to ensure compatibility and stability.Overall, pharmaceutical aerosols offer a promising approach to drug delivery, and ongoing research aims to optimize their formulation, design, and performance.