An Assessment of the Prevalence and Antimicro...

An Assessment of the Prevalence and Antimicrobial Susceptibility Status of Clinically Isolated Escherichia Coli

Author Name : Mehakpreet Kaur, Sanjay Parmar, Pankaj Kaul, Arindam Adhikary

ABSTRACT Escherichia coli(Escherichia coli)is a common bacterium that can cause infection in humans, and antimicrobial resistance in E. coli is a key public health issue. This study aimed to study the incidence and antimicrobial susceptibility status of clinically isolated Escherichia coli. A cross-sectional analysis was conducted on Escherichia coli isolates obtained from clinical specimens at the Department of Microbiology, Helix Path Labs, Mohali. Pus and urine samples were used for isolation of E. coli. Patient profiles including age, gender were noted. Antimicrobial susceptibility testing (AST) was executed by Kirby Bauer’s disc diffusion method and the results were analysed based onstandards of Clinical and Laboratory Standards Institute (CLSI). The result indicated that that the majority of the positive samples were female having urinary tract infections. AST revealed that Escherichia coliisolates were greatly resistant to Cotrimaxazole followed by Levofloxacin and Tobramycin, but susceptible to Ciprofloxacine followed by Fosfomycine. The result of AST showed variable resistance pattern among the Escherichia coli isolates. Many strains exhibited a high degree of sresistance to multiple antibiotics indicating the presence of multi-drug resistance among the isolates. The implications of these findings are crucial in guiding appropriate treatment strategies for Escherichia coli infections. Comprehending the pattern of antibiotic susceptibility of clinically isolated strains can help medical professionals choose antimicrobial treatments that work and stop resistant infection from spreading