Anti-Inflammatory and Antimicrobial Activity ...

ABSTRACT

Hemigraphis colorata has a long history of medicinal use in India. H. colorata has several pharmacological properties, including anti-inflammatory properties. The goal of this study is to see if an ethanolic extract of H. colorata ointment can reduce inflammation. Preliminary phytochemical, antioxidant activity, GC-MS, FTIR, antibacterial activity, and in vitro anti-inflammatory tests were performed in this study. In ethanol extracts of Hemigraphis colorata, phytochemicals such as alkaloids, flavonoids, glycosides, saponins, phenols, and tannins were found. The antioxidant activity of the ethanolic extract of leaves was substantial. The presence of ascorbic acid was detected at its peak by GCMS analysis of leaf extract, it serves as an antioxidant. The antimicrobial activity of a sequential extract H. colorata ointment were tested using the well diffusion method against gram-positive and gram-negative bacterial strains. The anti-inflammatory activity of H.colorata ointment is determined by protein denaturation method. In the south of India, the leaves are used as a traditional folk medicine to treat inflammation and wound healing activity. Many disorders linked to inflammation can be effectively treated using a natural substance derived from medicinal herbs. The traditional medication used to treat inflammation on the market has a number of negative side effects. There is a need to look for newer medications with fewer or no adverse effects as a result of these negative effects. Herbal medicines are much safer than synthetic drugs because around 1 lakh people die every year due to the toxic effect of synthetic drugs.