Formulation and Evaluation of Transdermal Pat...

Formulation and Evaluation of Transdermal Patch of Diclofenac Sodium

Author Name : Ms. Purnima Patel, Mr. Pankaj Kumar

ABSTRACT Tran’s dermal drug delivery has made an important contribution to medical practice. It is a medicated patch that delivers a specific amountof medication through the skin into the blood stream. An advantage of a transdermal drug delivery route over other types of medication deliveryis that the patch provides a controlled release of the medication into the patient, usually through either a porous membrane covering a reservoirof medication or through body heat melting thin layers of medication embedded in the adhesive. The present investigation was aimed toformulate transdermal films of non-steroidal anti-inflammatory drug, Diclofenac sodium using mercury substrate method and evaluated forphysicochemical parameters like thickness, weight variation, moisture uptake, moisture content, folding endurance, and drug content values.