Herbal Interventions for Enhancing Melanin an...

Herbal Interventions for Enhancing Melanin and its Production: A Systematic Review

Author Name : Nikita Bubera, Dr. Shrutika Patil, Shraddha Gawand, Saurabh Gadadhe, Ayush Parve, Satya Babu Palingi

ABSTRACT Melanin is a crucial pigment responsible for skin coloration, hair, and eyes, with significant roles in protecting against UV radiation and oxidative stress. Recent studies have explored the potential of herbal interventions to enhance melanin production, offering a natural approach to pigmentation disorders and skin health. This review examines various herbal extracts and their bioactive compounds known to stimulate melanogenesis. For instance, Merinda centifolia (Noni) and Curcuma longa (Turmeric) have shown promise due to their antioxidant properties and ability to influence melanocyte activity. Additionally, compounds like arbutin and ellagic acid found in plants such as Arbutus unedo and Punica granatum respectively, have been linked to melanin synthesis enhancement through various signalling pathways, including the mitogen-activated protein kinase (MAPK) and cyclic AMP (cAMP) pathways. Furthermore, traditional practices utilizing herbs like Ginkgo biloba and Aloe vera have been documented for their skin-rejuvenating properties, indirectly supporting melanin production. This herbal approach not only offers therapeutic benefits but also aligns with the growing preference for natural products in skincare. Future research should focus on the mechanistic understanding of these herbal compounds and their efficacy in clinical settings. Overall, integrating herbal interventions presents a promising avenue for enhancing melanin production, contributing to both cosmetic and therapeutic applications.