Impact of Vitamin B12 and Folic Acid in Sperm...

Impact of Vitamin B12 and Folic Acid in Sperm Concentration

Author Name : Dr. Lokesh. K, Dr. Borus Purushothaman, Dr. Yashmi Agwina Xavier, Veerammal, Dr. Suman Sharma

ABSTRACT The role of micronutrients, particularly Vitamin B12 and folic acid are the antioxidants, in which male fertility has garnered increasing interest due to their involvement in DNA synthesis, cell division, and methylation processes. This study explores the impact of Vitamin B12 and folic acid on sperm concentration, focusing on their potential to enhance spermatogenesis and improve overall sperm quality. Deficiencies in these vitamins have been linked to adverse effects on sperm concentration, leading to decreased fertility rates. Vitamin B12, a key component in cellular metabolism, aids in DNA synthesis and is essential for the maintenance of nerve health and the production of red blood cells. Its deficiency is associated with reduced sperm concentration and motility. Folic acid, a water-soluble B vitamin, is vital for nucleotide biosynthesis and methylation, both critical for sperm development. Folate deficiency has been shown to impair spermatogenesis and DNA stability, contributing to lower sperm counts and increased risk of infertility