Phytochemical Analysis and Anthelmintic Activ...

Phytochemical Analysis and Anthelmintic Activity of Phyllanthus Emblica Linn

Author Name : Ajay Kumar Yadav, Manisha Chandrakar, Rita Devi, Aakanchha Singh, Varsha Sahu, Khomendra Kumar Sarwa, Dron Kumar Sahu

DOI: https://doi.org/10.56025/IJARESM.2023.117231767

ABSTRACT

Phyllanthus emblica is a deciduous shrub used in the Ayurvedic medicinesystem and has been reported to boost defense against ailments. The different parts of these plants are used to manage a large number of health conditions such as liver disease, heart disease, ulcers, anemia, humanoids, and other diseases. The ethanolic leaf extract of Phyllanthus emblica was evaluatedfor its anthelmintic activity against the Pheretima posthuman(Indian adult earthworm).The fresh leafextract of thesewith different concentrations (30 mg/ml, 60 mg/ml, and, 100 mg/ml) was tested in invitro, to investigate the paralysis and death times of worms.The ethanolic extract showed concentration-dependent anthelmintic activity at all doses. Normal saline served as the control group while albendazole (20 mg/ml) served as the reference medication. The Ethanolic Leaf Extract of Phyllanthus emblica was found to possess vermifuge (paralysis) and vermicidal (death) activity at all dose levels.

Keywords: Phyllanthus emblica, Anthelmintic activity, Pheretima post human, Albendazole, Earthworms