Plant as a Potential Source of Heme Agglutini...

Plant as a Potential Source of Heme Agglutinin against the Human Blood Group System

Author Name : Bano Shabnam, Dr. Murtaza Hajoori

ABSTRACT Hemagglutinins are proteins that bind to specific carbohydrate antigens on red blood cells, causing them to agglutinate.These proteins have been extensively studied for their role in blood typing and compatibility testing. Plant-based hemagglutinins have emerged as a promising alternative to traditional sources, such as microbial and animal sources, due to their abundance, diversity, and potential therapeutic applications.This review explores the diversity of plant species that produce hemagglutinins and their specificity towards human blood group antigens. Plants such as legumes, grains, and fruits have been found to contain hemagglutinins with varying specificities, making them valuable tools for blood typing and compatibility testing.Furthermore,plant-based hemagglutinins have shown potential therapeutic applications. Their ability to bind to specific blood group antigens opens up possibilities for targeted drug delivery and immunomodulation. Additionally, plant hemagglutinins may have applications in cancer therapy, where they could be used to target specific antigens expressed on tumor cells.The use of plants as a source of hemagglutinins against the human blood group system represents an exciting area of research with significant implications for blood transfusion, transplantation, and targeted therapy. Further research is needed to fully explore the therapeutic potential of plant-based hemagglutinins and to develop safe and effective strategies for their use in clinical settings.