Plant-Derived Bioactive Compounds for Cancer ...

Plant-Derived Bioactive Compounds for Cancer Treatment

Author Name : Km Priti, Kalpana Sagar

DOI: https://doi.org/10.56025/IJARESM.2024.121024338

ABSTRACT Cancer is one of the most serious health issues that humanity has ever faced. It is a terrifying disease that requires a vigorous treatment regimen. After cardiovascular disorders, it ranks as the second leading cause of death. Chemotherapy is still the mainstay of care for many types of cancer. There are numerous synthetic anticancer medications available, but their adverse effects and drug interactions severely limit their clinical usefulness. The majority of chemotherapy medications currently in use for cancer are known to cause side effects that limit dosage, show non-selective toxicity against normal cells, and eventually develop resistance. Therefore, developing medications to treat cancer and other diseases is a significant clinical challenge. Plants are an excellent source of naturally occurring biologically active chemicals and their modified derivatives with enhanced activity and reduced toxicity can be used for cancer therapy. Due to their accessibility, affordability, low cost, minimal or non-existent side effects, and potential as anticancer agents, herbal medicines are currently gaining popularity. Natural plant components such as curcumin, turmeric, giloy, ashwagandha, aloe Vera, wheatgrass, black pepper, etc., have been utilized in phytomedicine to treat cancer. This review summarizes the anticancer activity of some herbal plants.