Review on the Role of Teneligliptin in the Ma...

Review on the Role of Teneligliptin in the Management of Diabetic Nephropathy

Author Name : Snehal Mahabade , Shravani Salunke , Dr. Mahesh M Deshpande

ABSTRACT Teneligliptin is a novel oral dipeptidyl peptidase-4 inhibitor for the remedy of type 2 diabetes mellitus. Diabetes is a worldwide fitness emergency of this century. Diabetic nephropathy is the maximum common microvascular trouble related to kind 2 Diabetes Mellitus. T2DM has been mentioned as a top etiological component in nearly forty five% of sufferers undergoing dialysis because of kidney failure. Life-style modifications; cessation of smoking, ideal control of blood glucose, blood stress and lipids are required to lessen the improvement of Diabetic Kidney disease. Currently, Dipeptidyl peptidase-4 (DPP-four) inhibitors are desired within the control of T2DM due to their mounted efficacy; favourable tolerability collectively with, low threat of hypoglycaemia; weight neutrality and handy as soon as-a-day dosage. Present proof indicates that linagliptin and teneligliptin may be used efficiently without dose modifications in patients with T2DM with renal impairment, collectively with surrender degree renal illness (ESRD). There can be a limited facts about teneligliptin specifically in T2DM sufferers with renal impairment.