Hypothyroidism correlation with anemia in adu...

Hypothyroidism correlation with anemia in adults

Author Name : Dr. Shilpi Sharma, Dr. Kesar Chayal

Anatomy of thyroid gland- The thyroid gland comprises two lobes united by an isthmus. It is situated in front of trachea between the suprasternal notch and cricoid cartilage. The thyroid gland weighs about 12 to 20 grams and is bigger in females than in males. Four parathyroid glands are situated back to each pole of thyroid gland, which secretes parathormone. Physiology of thyroid hormones- The principal hormones secreted by thyroid gland are T3 (Triiodothyronine) and T4 (Thyroxine). Thyroid hormones play a vital role in cell differentiation during development and maintain metabolic homeostasis in adults . The secretion of T3 and T4 are mainly controlled by Thyroid Stimulating Hormone. Thyrotropin releasing hormone (TRH) stimulates the secretion of T3 and T4. The hypothalamic secretion TSH and pituitary secretion of TRH are under negative feedback control of free T4 and free T3.