An Article Regarding the Disease Laughing Dea...

An Article Regarding the Disease Laughing Death

Author Name : R Manivannan, V Srividhya, TM Mouleeswaran, B Naveen, C Karthik

ABSTRACT

Kuru is aprogressive degeneration of the structure and function of the central nervous system or peripheral nervous system that was formerly widespread among the foreign citizens of Papua New Guinea that is incurable andthat can cause death or great damage. Kuru is a type of transmissible spongiform encephalopathy (TSE) induced by the transmission of abnormally folded proteins (prion proteins), leading to symptoms such as tremors and neurodegenerative loss of coordination. Kuru, which also shows shaking. The first human prion disease in Kuru was passed on to chimpanzees. Kuru is called as the Laughing death because the people who are affect with the kuru having the behavior of jerking and people in that place called the diseases as laughing death. It is the disease of contaminated human brain tissue, still the impact of the kuru in that place. Cannibalism is the main reason for the kuru, still most of tribes follows that cannibalism. In the eventual spread of Creutzfeldt-Jakob disease and the importance of bovine spongiform encephalopathy for human transmission, the discovery of the kuru opened new views of human medicine and was critical. One of the main contributors to the propagation of Kuru was biochemical and biological science of the 20^thcentury.

Key Words: Carleton, Chimpanzees, Kuru, Neuropathology, Prion diseases