Animal Models For Screening Anti-Anxiety Drugs: A Review

Author Name : Mr. Sufiyan Akhtar, Dr. V.V. Paithankar, Mr. J.V.Vyas, Dr. A. M. Wankhade

ABSTRACT

Animal models are extremely useful in understanding disease and in developing treatments for specific diseases. Animal studies are now widely acknowledged to play an important role in the understanding of anxiety disorders, as they contribute to current knowledge about the mechanisms and potential therapeutic approaches in anxiety. The anxiolytic impact of a novel substance can now be assessed using a variety of models and assays, or even in comparison to the standard medication. According to ethics, a new substance or medicine that may have pharmacological effects should first be evaluated on animals because they have physiologies similar to those of people. Prior to the addition of several strains of mice for the evaluation of anxiolytics due to their superior genetic potential to rats, behavioural tests for anti-anxiety drugs were initially conducted on rats. We've covered the most popular animal models in this review article for assessing the anti-anxiety impact. Anxiolytics are substances used to reduce anxiety effects brought on by any cause. The various parameter will be undertaken for the better and precise evaluation of anxiolytics.

Keywords:Anxiety, animal models, elevated plus maze, elevated zero maze, the light and dark box, open-field, hole-board, social interaction