Formulation and evaluation Herbal Drugs in Pa...

Formulation and evaluation Herbal Drugs in Parkinsons Disease

Author Name : Pakhare Nandlal Baliram, Miss R Shinde, Dr. Hingane L D

ABSTRACT

Parkinsonism (Parkinson's Disease) is one of the commonest progressive neurodegenerative disorder characterized by the loss of the nigrostriatal system's pigmented dopaminergic neurons with a subsequent drop in dopaming. Parkinson's Disease (PD) refers to such motor disorders such as resting tremor, muscle stiffness, and slow motion. Recent studies have shown that there has been an increasing interest in natural products particularly plants, for the treatment of Parkinson's disease. The anti-PD effects of these natural products are considered to be due to their regulation ability: development of reactive oxygen species, neuroinflammation, production of dopamine, excitotoxicity, metal homeostasis mitochondrial function, and cellular signaling pathways, all of which are disordered in the PD brain.

The herbal drugs therefore are safer than other drugs. Herbal medicine has its roots in ancient civilizations. It includes the usage of medicinal plants to cure disease and enhance general wellbeing.