Formulation and Evaluation of Citrullus Colocynthis Cream for Wound Healing

Author Name : Darade Pooja Bharat, Prof. Mr. Rokade. V. G, Dr. Hingane. L. D

ABSTRACT

Herbal treatment has been targeted in the study, as of their greater demand in market nowadays. Citrullus colocynthis distributed in UAE desert and other parts of the world and formulated in the pharmacological activity wound heal activity using excision wound. The grouped animals anesthetized different concentration with natural bees wax base as a Citrullus colocynthis cream (CCC). Asses and an excision wound was inflicted by cutting away a 30 mm full thickness of skin from a predetermined shaved area and kept as opened and treated topical once in a day. Citrullus colocynthis Cream shows significant effect wound area cured within a period of 11th day and wound area .

Citrullus colocynthis Cream showed healing of the open wound more significantly effective compare other natural creams.The ayurvedic name of bitter apple is indrawaruni . This plant tends to control kapha and pitta doshas . All parts of plant have some role in varieties of disorders and ailments. The fruits are bitter and cool so act as purgative, carminative antipyretic and tend to cure asthma tumors constipation and more.

Keywords: Citrullus colocynthis, incision wound, bees wax base cream.