Glimepiride estimation via Analytical Methods...

Glimepiride estimation via Analytical Methods an Overview of Developments and Approaches

Author Name : Sarthak Manoj Sambre, Chaitanya Balu Sahane, Ms. Akshata Bairagi

ABSTRACT Glimepiride, a popular Sulfonylurea antidiabetic medication, must be estimated using accurate and consistent analytical techniques across various biological matrices and formulations. A thorough summary of the current analytical methods used for Glimepiride estimation is given in this review, which includes chromatographic techniques such as gas chromatography (GC), ultra-performance liquid chromatography (UPLC), and highperformance liquid chromatography (HPLC). Furthermore included are capillary electrophoresis, spectrophotometric procedures, and sophisticated approaches like mass spectrometry. The paper emphasizes how these techniques can be used in pharmacokinetic and quality control research because of their sensitivity, accuracy, and suitability. Additionally, the difficulties in developing analytical methods and the factors of technique validation are emphasizedto guarantee precise and reliable Glimepiride measurement on various platforms.