Microneedles-Based Drug Delivery System; Des...

Microneedles-Based Drug Delivery System; Design, Development and Applications

Author Name : Kalpana, Kajal Rani, Simranjeet Kaur, Shezan Bhat, Aakrshan Kumar, Aditi Bhardwaj

ABSTRACT In transdermal medication delivery, microneedles (MNs) represent a paradigm shift that offers a practical solution to the substantial obstacles posed by the cutaneous interface .MNs are examined in this review as a cutting edge strategy for improving the management of dermatological pathologies. It examines the intricate structure of the dermis and draws attention to the drawbacks of conventional transdermal techniques, highlighting the benefit of MNs in delivering medications straight to the subdermal matrix without going via the stratum corneum .The discussion describes the various types of MNs, such as hydrogel, rigid, enclosed, vacant, and soluble forms. All types are distinguished its own advantages as well as uses. In addition to treating inflammatory dermatoses including psoriasis and atopic dermatitis, the treatise describes how MNs are used to cure wounds and reduce skin malignancies. The study also considers MNs' potential in the field of skin related as well as the growing popularity of cosmetic Microneedles preparations. Measurement, Drug effect, biological compatibility, Adherence of patient, disinfection, automation, or supervisory monitoring are some of the business obstacles to the medical application of Microneedle therapies that are outlined in the paper. In order to defeat such these challenges or entirely achieve Microneedles promise in handling dermal and enhancing patient care, it highlights the necessity of continued research, innovation, and regulatory harmonization.