International Journal of All Research Education & Scientific Methods

An ISO Certified Peer-Reviewed Journal

ISSN: 2455-6211

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NMPyTs is an efficient catalyst for the synth...

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NMPyTs is an efficient catalyst for the synth...

NMPyTs is an efficient catalyst for the synthesis of thiazolidine-4-one derivatives of Isoniazide.

Author Name : Amol V. Sapkal, Rahul R.Dhavse, Balaji R. Madje

ABSTRACT

An efficient, green and facile synthesis of thiazolidine-4 one derivatives has been described on reaction with mercaptoacetic acid, and Schiff’s bases in(Isoniazide and substituted benzaldehyde) using recyclable ionic liquid (NMPyTs) as a catalyst and ethanol. This protocol offers the significant advantages in terms of simplicity, very good yields, simple workup procedure, short reaction time and this method is eco-friendly benign.

Key Words: -Mercaptoacetic acid, ionic liquid and Schiff’s bases of Isoniazide.