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Novel Synthesis of pyrimidones, Pyrazolones by using Chalcones
Author Name : AlphonsusD’souza* ,Venuprasad, PrashantNayak*, Prasanna Shama K, Bharath Raj K.C, Rajesh K.S, Zeenafernandes
ABSTRACT Chalcones(3)were synthesised by using 4methyl amino benzaldehyde and 1-(3hydroxyphenyl)ethanone by using NaoH as catalyst. 3 was converted into pyrazoles(6) by using hydrazine hydrate, as well as compound 3 was converted into pyrimidones by using urea and thioureaand compounds were screened for antibacterial activity.