Phytochemical and Pharmacological Investigati...

Phytochemical and Pharmacological Investigation on Glinus Oppositifolius Linn Anti-Diabetic Activity

Author Name : Mr. Datir Mahendra Baban, Dr. Mrunal Krishnarao Shirsat

ABSTRACT In the analysis of its potential to prevent diabetes, the effects of petroleum ether, chloroform and methanol, fast bloo d glucose and blood biochemical analyzes in streptozotocin diabetic rats were investigated. Of all three extracts, oral administration of 500 mg/kg of methanol extract significantly reduced glucose overload and streptozotocin in norm al, normal rats after 15 days of treatment. ; Petroleum ether and chloroform extract did not show any significant eff ect on three groups of rats at an oral dose of 500 mg/kg. Simultaneous histological studies on the pancreas of these a nimals first demonstrated the comparative regenerative capacity of methanol extracts necrotic by streptozotocin. Th e results showed that it had a positive effect on diabetes in the experimental diabetes model.