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Phytochemistry and Antioxidant Potential of Symplocos Racemosa Bark Extract
Author Name : Samala Gowthami, Sudhakar Poda
ABSTRACT The study aimed to reveal the phytochemistry and antioxidant potential of Symplocos racemosa bark extract. S. racemosa bark from Tirupathi forests, Western Ghats, India, was collected, cleansed and dried in a vented oven at 40°C for three weeks. The bark was ground into powders using a laboratory blender and active constituents was extracted using the Soxhlet extraction process. The study revealed that the qualitative phytochemical profile of S. racemosa bark extract comprises alkaloids, carbohydrates, flavonoids, phenolics, glucosides, sterols, fatty acids, coumarins, and terpenoids. The quantitative study revealed that S. racemosa bark extract contains total phenolics and flavonoids of 16.33 ± 2.43 mg/g of gallic acid equivalents and 24.26 ± 1.69 mg/g of rutin equivalents, respectively. ”. S. racemosa bark extract showed dose-dependent DPPH and ABTS radical scavenging activity up to the tested level of 150 µg/mL. The EC50 value for S. racemosa bark extract for DPPH and ABTS is determined as 88.67 ± 3.05 and 91.78 ± 5.27 µg/mL, respectively.According to our investigation, S. racemosa bark extract contains useful secondary metabolites. S. racemosa bark extract has significant antioxidant activity, which is frequently linked to phenolic and flavonoid compounds. As a result, S. racemosa bark extract may be useful in the treatment of a few conditions linked to oxidative stress, including cancer, heart disease, neurological conditions, etc.