Synthesis and Characterization Antimicrobial ...

Synthesis and Characterization Antimicrobial Activities of Schiff Base Complexes of Cu (II), Co (II) and Ni (II)

Author Name : M. Shyamala Devi Thankachi, S. Sharmila Juliet, J. Anix Joel Singh

ABSTRACT

The complexes STC, STCO, STN of Cu (II), and Co (II) and Ni (II) ions with a Schiff base (ST) derived from salicylal dehyde  and  sulfathiazole have been investigated. The resulting complexes were characterized by UV/Vis IR spectral studies, elemental analysis, molar conductance, XRD and antimicrobial activity. The molar conductance measurement indicates that the complexes were non electrolytes. The IR data shows that complexes were mono basic ligand with NO bidentate sites. The XRD study shows that the complexes were microcrystalline in nature, the antimicrobial activity of the complexes were tested against the bacterial, E.coli, Pseudomonous aeroginosa,  Staphylococcus aureus and fungi Candida by the Disc diffusion method. The complex shows stronger antimicrobial activity than the free ligands.

Keywords: Schiff base, Sulfathiazole , Antifungal and Antibacterial Activities